When submitting manuscripts to many journals, there is an opportunity to suggest reviewers for the manuscript. I have found that failure to do so can result in one or more reviews where the reviewer obviously had no idea what the heck was going on. However, as I have never suggested anyone as a reviewer, I’m not really sure how this works. Specifically, if one is to suggest a particular person as a reviewer, should one ask that person first? On the one hand, asking someone to review a paper is dobbing them in for a considerable amount of work, and asking for a review without prior contacts seems a bit like listing someone as a personal reference without asking. ON the other hand, the peer review system is supposed to be anonymous (you in the back, stop laughing), so in theory one could interpret potential reviewer solicitation as a breach of confidentiality. My gut feeling would be to ask people with whom I am comfortable corresponding, and to be very equivocal about putting any other names forward (e.g. Dr. X is knowledgeable in the field, but I have no idea whether he has the time or interest to review the paper). Any suggestions?